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Tosti A, Bardazzi F, Piraccini BM, Fanti PA. Idiopathic trachyonychia (twenty-nail dystrophy): a pathological study of 23 patients. Br J Dermatol 1994; 131: 866–72. 18. Alkiewicz J, Górny W. Zur Klinik und Histopathologie der Längsfurchen der menschlichen Nagelplatte. Arch Derm Syph (Berl) 1937; 175: 467–75. 19. Peluso AM, Tosti A, Piraccini BM, Cameli N. Lichen planus limited to the nails in childhood: case report and literature review. Pediatr Dermatol 1993; 10: 36–9. 20. Takeuchi Y, Iwase N, Suzuki M, Tsuyuki S.

The genetic defect in families with short fingers due to a congenital lack of the terminal phalanx and thus lack of nail development has recently been elucidated. 37 A syndrome of anonychia and deafness is called the DOOR syndrome. 34) is due to a mutation of the LMXB2 gene, which is responsible for anterior–posterior orientation during embryonic development and kidney development. Besides nail changes, a hypoplastic or completely lacking patella, iliac horns, severe nephropathy, and corneal alterations of the eyes may be present.

Zaias N. The nail in lichen planus. Arch Dermatol 1970; 101: 264–71. 26. Cornelius CE 3rd, Shelley WB. Permanent anonychia due to lichen planus. Arch Dermatol 1967; 96: 434–5. 27. Haneke E. Isolated bullous lichen planus of the nails mimicking yellow nail syndrome. Clin Exp Dermatol 1983; 8: 425–8. 28. Fanti PA, Tosti A, Morelli R, Galbiati G. Nail changes as the first sign of systemic amyloidosis. Dermatologica 1991; 183: 44–6. 29. Mancuso G, Fanti PA, Berdondini RM. Nail changes as the only skin abnormality in myeloma-associated systemic amyloidosis.

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