Download Advances in Forensic Applications of Mass Spectrometry by Jehuda Yinon PDF

By Jehuda Yinon

The mass spectrometer is now a vital part of each forensic laboratory. this system ends up in reduce detection limits, extra trustworthy id, and bigger analytical accuracy. Exploring the most recent advancements within the box, Advances in Forensic purposes of Mass Spectrometry presents a finished reference consultant to forensic purposes utilizing glossy mass spectrometry innovations. The textual content positive aspects equipment constructed from complicated instrumentation, drug detection and toxicological research, technique of purposes of reliable isotope ratios, and systems for research of explosives in post-blast residues.

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Gaillard, Y. , Screening and identification of drugs in human hair by high-performance liquid chromatography-photodiode-array UV detection and gas chromatography-mass spectrometry after solid-phase extraction. A powerful tool in forensic medicine, J. Chromatogr. A, 762, 251, 1997. 37. Gaillard, Y. , Use of high-performance liquid chromatography with photodiode-array UV detection for the creation of a 600-compound library. Application to forensic toxicology, J. Chromatogr. A, 763, 149, 1997. 38.

51. H. , Postmortem drug analysis: analytical and toxicological aspects, Ther. , 24, 199, 2002. 52. , Chapter 3, this volume. 53. , Determination of drugs of abuse in meconium [review], J. Chromatogr. B, 713, 137, 1998. 54. , Detection of drugs of abuse in nails, J. Anal. , 22, 314, 1998. 55. , Detection of non-steroidal anti-inflammatory drugs in equine plasma and urine by gas chromatography-mass spectrometry, J. Chromatogr. A, 719, 251, 1996. 56. H. , Drug Metab. , 24, 5, 1992. 57. , Wiley-VCH, Weinheim, Germany, 2000, 3.

181 Common trimethylsilylation leads to best GC/MS sensitivity. 8 Nonsteroidal Antiinflammatory Drugs (NSAIDs). Nonopiod analgesics are among the most commonly consumed over-the-counter preparations all over the world. Besides acetylsalicylic acid, paracetamol, and pyrazole derivatives, so-called NSAIDs, are used against acute and chronic pain, inflammation, and fever. Altough NSAIDs are perceived to be safe drugs, they may lead to severe toxic effects in case of acute overdosage or in case of chronic abuse.

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