By R. John Mayer, Aaron J. Ciechanover, Martin Rechsteiner
The second one quantity in a brand new sequence devoted to protein degradation, this publication discusses the mechanism and mobile capabilities of distinctive protein breakdown through the ubiquitin pathway.
Drawing at the mixed wisdom of the world's best protein degradation specialists, this useful reference compiles info at the proteasome-mediated degradation steps of the ubiquitin pathway. as well as proteasomal functionality and law, it additionally provides the most recent effects on novel participants of the ubiquitin superfamily and their function in mobile regulation.
Further volumes within the sequence conceal the functionality of ubiquitin-protein ligases, and the jobs of the ubiquitin pathway in regulating key mobile tactics, in addition to its pathophysiological ailment states.
Required studying for molecular biologists, mobile biologists and physiologists with an curiosity in protein degradation.
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