By Amitava Dasgupta
Written in a guide kind with particular equipment and tips about getting rid of fake confident and fake unfavorable effects, this ebook is a realistic advisor to the particular mechanisms of such occurrences.
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Additional info for Handbook of Drug Monitoring Methods: Therapeutics and Drugs of Abuse
Example text
Other Information Dosage regimen Time of taking dosage Type of specimen (serum, urine, saliva, other body fluid). Number of specimens (if more than one) and type of drug concentration requested (total vs. free) Time of specimen collection (peak vs. trough) Time of last dose Concentration of the drug Pharmacokinetic parameters of the drug 22 Dasgupta Although free drug concentration can be predicted from traditionally measured total drug concentration (free + protein-bound drug), under certain disease conditions, such as uremia and hepatic impairment, free drug concentration may not be predicted from total drug concentration because of impairment of the protein-binding ability of serum for these anticonvulsants.
Berkovitch M, Dafni O, Leiboviz A, Mayan H, et al. Therapeutic drug monitoring of theophylline in frail elderly patients: oral compared with nasogastric tube administration. Ther Drug Monit 2002; 24: 594–597. 134. Sashidharan SP. The relationship between serum lithium levels and clinical response. Ther Drug Monit 1982; 4: 249–264. 135. Gadallah MF, Feinstein EI, Massry SG. Lithium intoxication: clinical course and therapeutic considerations. Miner Electrolyte Metab 1988; 14: 146–149. 38 Dasgupta 136.
Although the dispositions of many antibiotics are altered in patients with cystic fibrosis, patients with cystic fibrosis exhibit a disposition of vancomycin similar to that exhibited by healthy adults, and thus, cystic fibrosis does not alter pharmacokinetic parameters of vancomycin (155). Reference ranges and costs for monitoring antibiotics are summarized in Table 10. 7. Therapeutic Drug Monitoring of Antiretroviral Drugs HIV is the virus that causes acquired immunodeficiency syndrome (AIDS).