By Evelyne Sernagor, Stephen Eglen, Bill Harris, Rachel Wong
This complicated textual content takes a developmental method of the presentation of our present figuring out of ways vertebrates build a retina. Written via specialists within the box, all the seventeen chapters covers a particular step within the method, targeting the underlying molecular, mobile, and physiological mechanisms. there's additionally a distinct part on rising applied sciences, together with genomics, zebrafish genetics, and stem mobilephone biology which are commencing to yield vital new insights into retinal improvement. essentially aimed toward execs, either biologists and clinicians operating with the retina, this booklet offers a concise and up to date view of what's identified approximately vertebrate retinal improvement. because the retina is 'an approachable a part of the brain', this e-book can also be beautiful to all neuroscientists attracted to improvement, as approaches required to construct this exquisitely geared up process are finally proper to all different components of the primary anxious procedure.
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Example text
Fate map of the chicken neural plate at stage 4. Development, 129, 2807–22. Gallagher, B. , Hainski, A. M. and Moody, S. A. (1991). Autonomous differentiation of dorsal axial structures from an animal cap cleavage stage blastomere in Xenopus. Development, 112, 1103–14. , Reneker, L. W. et al. (2002). Mutually regulated expression of Pax6 and Six3 and its implications for the Pax6 haploinsufficient lens phenotype. Proc. Natl. Acad. Sci. U. S. , 99, 8719–24. , Patel, M. and Sive, H. (1998). Determination of the zebrafish forebrain: induction and patterning.
The eye field transcription factors (EFTFs) (Xenopus homologues) including the origin of their abbreviated names and the transcription factor family to which they belong. 3 Eye field transcription factors have overlapping expression patterns during eye field formation. , 2004). Two Pax6 (Pax6a and Pax6b) and three Rx (Rx1, Rx2 and Rx3) homologues have been identified in fish. 5. The location of the presumptive eye field is indicated with a black dashed line. hpf, hours post-fertilization. For colour version, see Plate 1.
The effect of the removal of the median and lateral areas of the anterior end of the urodelan neural plate on the development of the eyes (Triton teniatus and Amblystoma punctatum). J. Exp. , 54, 249–90. Adelmann, H. B. (1929b). Experimental studies on the development of the eye. II. The eye-forming potencies of the urodelan neural plate (Triton teniatus and Amblystoma punctatum). J. Exp. , 54, 291–317. Adelmann, H. B. (1930). Experimental studies on the development of the eye. III. The effect of the (‘Unterlagerung’) on the heterotopic development of median and lateral strips of the anterior end of the neural plate of Amblystoma.