By David Freedman, Robert Pisani, Roger Purves
Well known for its transparent prose and no-nonsense emphasis on center ideas, records covers basics utilizing actual examples to demonstrate the techniques.The Fourth variation has been conscientiously revised and up-to-date to mirror present info.
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Extra resources for Statistics, 4th Edition
Example text
They characterize a relatively small number of important dermatologic disorders, so are extremely helpful diagnostic findings. Vesicles and bullae occur either intraepidermally or subepidermally. The differential diagnoses are different for intraepidermal and subepidermal blisters, so it is important to try to distinguish them. Clinically, one clue is the fragility of the blister. Because of their more substantial roof, fresh subepidermal blisters are tense and less easily broken, whereas intraepidermal bullae are flaccid and easily rup tured.
These diseases include psoriasis, dermatitis, pityriasis rosea, pruritus, vitiligo, and mycosis fungoides. However, these beneficial effects must be weighed against the potential adverse effects, which include sunburn, aging, and skin cancer. Excessive exposure to solar irradiation results acutely in sunburn and chronically in premature aging (Fig. 4) and carcinogenesis. These adverse effects may be prevented with the use of topical sunscreens and protective clothing, and by avoiding midday exposure when sunlight is most intense.
Inclusion bodies are not well seen, but the finding of multinucleate giant cells is diagnostic for infection with either herpes simplex or varicella-zoster virus (Fig. 8). 36 S E C T I O N 1 C H A P T E R 4 D ermat o l o g i c T herap y a n d P r o ced u re s present, they should first be removed so that the underlying exudate can be swabbed and cultured. More invasive procedures are required for deeper bacterial infections. 5–1╯mL of non-bacteriostatic saline. Cultures of skin biopsies may also be rewarding, especially for mycobacterial infections of the skin.